J Clin Rheumatol. 2014 Apr;20(3):146-50. doi: 10.1097/RHU.0000000000000089. Sympathetic nervous system dysfunction in fibromyalgia, chronic fatigue syndrome, irritable bowel syndrome, and interstitial cystitis: a review of case-control studies.Martínez-Martínez LA1, Mora TVargas AFuentes-Iniestra MMartínez-Lavín M.

After finding that autonomic dysfunction was common in ME/CFS, FM and related disorders, the authors recommended trying a variety of means to restore ‘autonomic balance’

A review of almost 200 published papers on sympathetic nervous system functioning in fibromyalgia, chronic fatigue syndrome, irritable bowel syndrome, and interstitial cystitis indicated that 72% of the studies found some sort of SNS dysfunction was present. Most found sympathetic nervous system over-activation but 7% found parasympathetic nervous system over-activation.

The review suggested autonomic nervous system problems could underlie these often co-morbid disorders. They recommended trying pharmacological and nonpharmacological measures to try and restore ‘autonomic balance’.

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