Is Jarred Younger online doing a Q&A as I write this? Does anyone know how I find it on line? Thank you!
Thank you Cort. I have it ready and waiting
http://www.cortjohnson.org/forums/threads/younger-pain-and-fatigue-lab-expands-live-youtube-event-on-thursday-march-3rd.3811/#post-13485
I think it's in about an hour and 30 minutes
What were your questions?Wow, what a waste that was. Just filled with chit chat. Moderator skipped my questions.
Every MECFS study that has looked for oxidative stress has found it in spades. Shungu believes it may play a huge role in the lactate he's found in the brain. I have no doubt that it plays a role - but what is causing it? Inflammation? Hypoxia? A damaged antioxidant system? ???One about how LDN only works with pain because it increases endorphins so why not just give the patient Opioids.
And are you investigating the role of Oxidative Stress at all? Since LDN reduces Oxidative stress, would not finding the source of Reactive Oxygen Species be more of a priority?
There is no one cause, that is the key. The way to find out where is though looking at genetics, diet, lifestyle, the whole thing. And the cure is finding the cofactors you need to take to stimulate enzyme activity, be it neurotransmitters or antioxidation, and be on the diet you need to be on to reduce ROS and neurotransmitters.Every MECFS study that has looked for oxidative stress has found it in spades. Shungu believes it may play a huge role in the lactate he's found in the brain. I have no doubt that it plays a role - but what is causing it? Inflammation? Hypoxia? A damaged antioxidant system? ???
YouTube of Q and A
"Particularly interesting is his hypothesis (26 min 40 sec in) that inflammation in the central nervous system drives a number of conditions including ME/CFS, increasing brain temperature by around 1°C.
The lab’s early experiments to measure brain temperature by MRI in ME/CFS and rheumatoid arthritis have had promising results, and the possibility that brain temperature increases are related to decreases in brain blood flow will be investigated using arterial labelling (32.35)
ThanksPS the Alabama accent of the presenter is a hoot!