Founder of Health Rising and Phoenix Rising
Fascinating article on NPR on Infection and Depression
I reported on this little tidbit earlier in a blogSymptoms Of Mental And Physical Illness Can Overlap
Late last year, Turhan Canli, an associate professor of psychology and radiology at Stony Brook University, published a paper in the journal Biology of Mood and Anxiety Disorders asserting that depression should be thought of as an infectious disease. "Depressed patients act physically sick," says Canli. "They're tired, they lose their appetite, they don't want to get out of bed." He notes that while Western medicine practitioners tend to focus on the psychological symptoms of depression, in many non-Western cultures, patients who would qualify for a depression diagnosis report primarily physical symptoms, in part because of the stigmatization of mental illness.
Then there's this. I would bet dollars to donuts that something like this is going on in ME/CFS and fibromyalgia in some people...A Danish study published in JAMA Psychiatry in 2013 looked at the medical records of over 3 million people and found that any history of hospitalization for infection was associated with a 62 percent increased risk of later developing a mood disorder, including depression and bipolar disorder.
At the end of the article the consensus seems to be with some people, yes, infection/inflammation is causing their depression...Dr. Roger McIntyre, a professor of psychiatry and pharmacology at the University of Toronto, tells Shots that he believes an upset in the "immune-inflammatory system" is at the core of mental illness and that psychiatric disorders might be an unfortunate cost of our powerful immune defenses. "Throughout evolution our enemy up until vaccines and antibiotics were developed was infection," he says. "Our immune system evolved to fight infections so we could survive and pass our genes to the next generation. However, our immune-inflammatory system doesn't distinguish between what's provoking it."
McIntyre explains how stressors of any kind — physical or sexual abuse, sleep deprivation, grief — can activate our immune alarms. "For reasons other than fighting infection, our immune-inflammatory response can stay activated for weeks, months or years and result in collateral damage," he says.