Yes, and I do have small-fiber neuropathy. Burning is one of my worst manifestations. When it's bad is when I'm most curled-up as if I have the flu (combined with extreme fatigue, migraine, and myalgias). Sometimes I've wondered if males are more prone to burning, since males are supposedly less likely to manifest FM trigger points (do some males experience burning instead?).
I describe it not so much as on the surface of the skin, but as if I have a bad sunburn about a half-inch below the surface -- all over my body. It is not necessarily connected to exercise, but it's guaranteed after especially poor sleep.
It worsens through the day -- seemingly an extension of ordinary neuropathic symptoms (numbness, tingling, bottom-of-the-feet burning etc). As it progresses, it gains energy, so that instead of a static sunburn feeling, it's more like molten lava flowing under my skin. Then, at it's worst, it becomes "electrical."
Duloxetine, for me, targets it directly (but helps nothing else). I've been taking Cymbalta for about 3/4 of a year (90mg), and it helps tremendously, but in recent months the burning has been returning (seemingly connected to an experiment with Nuvigil, which my body rejected). So, since then, I've been experimenting with tapering off the duloxetine and replacing it with tianeptine, NALT, octopamine, picamilon -- trying to pinpoint the source of the burning.
My suspicion is that norepinephrine problems are at the root of the burning (not so much serotonin) -- so if i can move away from such a sweeping SNRI as duloxetine and target the problem more specifically I might, hopefully, also find ways to regain energy. (It's possible the duloxetine makes me sleepier during the day.) But I'm still in the early stages of experimentation.
Interesting to see a possible connection with lactic acid buildup. I have excess uric acid (and gout), as well as severe restless legs -- which all feels somehow connected.
