Orthostatic Intolerance Dominate Inheritance

Gail C

Member
Conclusions

Familial occurrence and vertical transmission of autonomic dysfunction in 16 families suggests a novel genetic syndrome with dominant transmission, incomplete penetrance, and skewing of the sex ratio. Elucidation of potential genetic contributions to orthostatic intolerance may inform therapeutic management and identification of individuals at risk. Adolescent evaluation should include identification and treatment of potential at-risk relatives.

http://www.pedneur.com/article/S0887-8994(16)30419-2/abstract
 

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