Marian Lemle was the first to propose people with chronic fatigue syndrome were in a hypometabolic - hibernation-like state. She proposed that the state was probably protective and driven by hydrogen sulfide metabolism.
Use the download button on the upper right to get the paper.
Lemle's 2008 testimony to the CFSAC committee provides a good introduction to her hypothesis.
- Lemle published her hypothesis in Medical Hypotheses in 2009.
- Check out a 2009 interview with Marian here.
Hydrogen Sulfide Induces Hibernation State in Chronic Fatigue Syndrome (ME/CFS) 2016-09-03
Lemle's 2007 hypothesis paper proposes hypometabolic state present in ME/CFS