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  1. S

    Hanson's Metabolomics ME/CFS Study Validates Naviaux's Core Finding

    Given the major studies being done on this, a meta analysis on the 5+ studies mentioned (albeit in a few years time) will be very interesting.
  2. S

    The Blood Volume Paradox in Chronic Fatigue Syndrome (ME/CFS) and POTS

    Yes, to start with, Kunihisa Miwa was a co-author of the Myalgic Encephalomyelitis International Consensus Criteria... https://www.researchgate.net/profile/Kunihisa_Miwa
  3. S

    Reversing Alzheimer's: What Could it Mean for Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia?

    A small number of case studies? It's interesting, but I'm fairly jaded these days, I don't get excited over uncontrolled pilot studies.
  4. S

    Jared Younger CDC Talk Tomorrow To Bring Good News?

    New study from Jarred Younger and colleagues. Not ME specific, but: Association of Leptin with Body Pain in Women (sample size of over 5000) http://online.liebertpub.com/doi/10.1089/jwh.2015.5509
  5. S

    The Weirdiness of Walking and Exercise

    Ebike! Twice the fun, half the fatigue. I actually got substantially fitter through at one point, but same experience as you - no decrease in fatigue at all, still the same long payback period.
  6. S

    FOIA Indicates Lack of Interest Dogs Chronic Fatigue Syndrome Field

    Why don't they take an active role in building research capacity and encouraging new people into the field as they have done previously for AIDS, cancer etc? (and in Australia, conditions like Diabetes, Asthma have been made "national priorities")
  7. S

    Genes Highlight Inflammation and Mast Cells in Fibromyalgia

    Heatshock proteins being the most significant finding is interesting... There is a potential for more than a few interesting hypotheses there, I hope someone follows it up.
  8. S

    Resource Consumer Reports Recommends Generics over FDA Approved Drugs for Fibromyalgia

    I have seen such studies and they aren't exactly of the highest quality (some are from the ancient past - the 1980s!).
  9. S

    Resource Consumer Reports Recommends Generics over FDA Approved Drugs for Fibromyalgia

    Consumer Reports seem to be missing the point - those 'generic' drugs have different effects than the name-branded drugs. Secondly. paroxetine-IR and amitriptyline are unlikely to be effective for many patients. And amitriptyline has significant side effects (for me: bad POTS symptoms)...
  10. S

    End ME/CFS Severe Patient Study Turns to the Mitochondria

    I wonder how that is going?
  11. S

    Long-term methylphenidate intake in chronic fatigue syndrome

    Methylphenidate is heavily restricted in Australia - requires hospital authority from memory, and in turn requires an adult ADHD diagnosis. No off label prescription. High placebo effect LOL. That's why we have placebo controlled trials in the first place - to control for unexpected biases.
  12. S

    Poll Have Your ME/CFS and/or FM symptoms gotten better or worse since you first became ill?

    I am thinking something else... But still along the lines of autoimmune illness - also given that my rapid onset matched that of an acute autoimmune syndrome like GBS (triggered by vaccination - severe lower limb weakness, difficulty swallowing etc - I've never had any of the common infectious...
  13. S

    Poll Have Your ME/CFS and/or FM symptoms gotten better or worse since you first became ill?

    Worse - including new symptoms - constant eye pain, deterioration of eye sight etc. (to clarify, I've had ME since my youth, and had excellent vision for many years, but my eyes started declining at the age of 30)
  14. S

    Vegan Doctors

    Most of us take all sorts of supplements, what is the big deal with B12 supplements? In fact many omnivores I know still need to take B12 supplements.
  15. S

    ME/CFS stories on HuffPost Contributor platform

    This is disappointing. Especially the “noindex nofollow” BS. We deserve better.
  16. S

    Functional Somatic Syndromes" (ME/CFS/FM, etc.) As Serious As other Medical Conditions

    That is not a theory, nor even a hypothesis, it's a vague statement that has not specific testable consequences. If we continue to believe BS hypotheses with no evidence, then we'll never get there. If we actually try to dig deeper and find the truth, then we might. If such models have...
  17. S

    Functional Somatic Syndromes" (ME/CFS/FM, etc.) As Serious As other Medical Conditions

    I'm assuming that no one has shown a credible mechanism yet. By the way, I know a few ultraendurance athletes, and well, I don't think much of Noakes... Both Noakes and Boksem are vague on how the feedback mechanisms are invoked. Oh look, some brain studies pointing to all sorts of places in...
  18. S

    Functional Somatic Syndromes" (ME/CFS/FM, etc.) As Serious As other Medical Conditions

    Which are mediated (biologically) how? (rhetorical question) I'm surprised that anyone cares about effect sizes when there is no control. As Neuroskeptic said when specifically asked about this: generally that's meaningless. That's why you need a control. Within-group D = natural improvement...
  19. S

    Functional Somatic Syndromes" (ME/CFS/FM, etc.) As Serious As other Medical Conditions

    How? While such factors may well be risk factors, they are neither necessary, nor sufficient to trigger or maintain the illness. I've looked hard for such mechanisms in the literature for years and haven't seen anything I'd consider convincing. Hence I'm not so excited about discussing such...
  20. S

    Vegan Doctors

    Yes, you guessed correctly. I'm not an athlete (I surely would be a cyclist and runner if not for having ME as a teen!), but I know a few cyclists & runners!

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