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Autonomic correlations with MRI are abnormal in the brainstem vasomotor centre in Chronic Fatigue Syndrome
Highlights
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For the first time in CFS, we performed MRI regressions with steady state BP and HR.
•
Vasomotor centre, midbrain and hypothalamus correlations were abnormal in CFS.
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MRI group comparisons between CFS and controls detected no differences.
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Regulatory nuclei and peripheral effectors/sensors appear to function correctly.
•
Signalling between brainstem/midbrain regulatory nuclei appears to be impaired.
http://www.sciencedirect.com/science/article/pii/S2213158216300584
- Leighton R. Barndena, b, , , ,
- Richard Kwiatekc, ,
- Benjamin Croucha, ,
- Richard Burnetd, ,
- Peter Del Fantee,
Highlights
•
For the first time in CFS, we performed MRI regressions with steady state BP and HR.
•
Vasomotor centre, midbrain and hypothalamus correlations were abnormal in CFS.
•
MRI group comparisons between CFS and controls detected no differences.
•
Regulatory nuclei and peripheral effectors/sensors appear to function correctly.
•
Signalling between brainstem/midbrain regulatory nuclei appears to be impaired.
http://www.sciencedirect.com/science/article/pii/S2213158216300584