Yes, the glutamate is likely a part of it. I had scallops and mushrooms one night and had a bad migraine the next day despite my 100 mg oxaloacetate. I looked up glutamate in those foods and the penny dropped. It led me down the track of a low glutamate diet. That seems to help keep the migraines at bay. It is such a godsend after daily intractable migraines for years. It’s a major quality of life boost.Interesting that the 100mg worked so well for your migraines! It makes me wonder if at lower doses it's doing more for neuroinflammation/glutamate scavenging rather than raw ATP production. Good to know it doesn't always take the massive 1000mg+ study doses to see some benefit.
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