I was also able to learn, quite recently, that there is now a range of digestive enzymes which can be purchased which break down gluten proteins in order to reduce the severity of symptoms in those who choose not to adopt a gluten free diet. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400306/
If someone has Celiac, this is a path to new autoimmune diseases and eventual cancer.
Enzymes aren't new. They were once the only way for people to reduce harm in gluten sensitive diseases. There are several diseases other than Celiac that medically require a gluten free diet. Gluten Ataxia and Ehlers-Danlos Syndrome for instance. Most people with Crohn's disease also keep gluten free (but that's about 0.2% of the population, people with active Celiac are 1-2% of the population worldwide).
Enzymes were abandoned when the definition of Celiac was finalized to be tTg-IgA activation. That happened in the 1970s. In the 1950s through 1970s, people were offered enzymes and ALSO told to stay away from gluten sources, or eat a limited diet in the winter when they'd be more likely to eat bread or staples that use flour. Enzymes are only recently being marketed as an alternative to gluten free. They weren't, previously.
Enzymes are basically a scam because old type enzymes were never meant to be used alone, and the new types have way too many open questions.
None of the questions have been adequately answered and remain in the hypothetical stage of science. If you want the long version of new
science on enzymes, this is a decent primer: https://www.frontiersin.org/articles/10.3389/fped.2019.00193/full
Your link was good too, but note that it's hypothetical, not applied yet.
There are open questions...
Like whether they are contaminated with gluten or is it a false positive? https://www.glutenfreewatchdog.org/...tive-enzyme-supplements-a-very-brief-summary/
And should they be considered "gluten free" if grown on gluten media?
A concerned consumer reached out to Gluten Free Watchdog about this product. GFWD contacted the manufacturer asking about the source of wheat. The manufacturer reply stated: “The product does not contain any wheat or gluten. The enzyme used in our product is grown on fermented wheat so we are...
Enzymes for people with Celiac (or other required medical diet users)? Never.
For anyone who just has sensitivity to gluten, maybe. If they also try to avoid gluten, it may be OK.
This is a deep rabbit hole you can spend months reading about and still not get an answer.
There are tons of extremely helpful websites to help people with a required gluten free diet. Generally, good websites consider enzymes to be a taboo suggestion because it's too dangerous for people with Celiac Disease.
480+ gluten free recipes that all use just 1 CERTIFIED gluten free flour -- that GF consumers have voted #1 SIX TIMES! Mixes too! And of course, JULES
I've had celiac disease since 2008. I started this website in 2011 to be a resource for the gluteb-free community and for my own sanity.
(Yes you can still have bagels.)
Absolutely real sourdough bread.
The absolute easiest and cheapest way to get a GF bread mix right now.
You don't need to wait for a doctor to order testing if you can afford the test out of pocket. Take the result to a doctor instead. Make sure you're still eating gluten at the time you take that test, and make sure you're not using enzymes for a week before taking the test. If the result is positive, take it to a gastroenterologist and ask for an endoscopy. Only people who've had endoscopy-proven Celiac get benefits like, being part of experimental medicine trials, or getting social security if Celiac makes you unable to work.
I know this is TMI but I feel it's imortant to have a full answer to the Enzyme question. Enzymes are the source of a lot of online flame wars.