Funny! I had forgotten (but you reminded me with this thread) that I have the very same natural thermal salts and I had used them only a couple of times but they've expired now...if that's possible(?!). I also have alginate plus for the purpose of detox (can't report on it as I had good intentions but never used it...was a little afraid of it!). My life hasn't made room for me to really focus on it yet, though. Thanks for the book reference. I'll definitely look into it. I had formerly reduced carbs and generally do keep an eye on not over-doing them but the whole CFS gut scenario became such a train wreck for me that I had to consume some carbs to offset my body's reaction to fiber/veggies etc. Paleo-style eating had been my go-to but it began to disagree with my gut (I eat non-gmo, organic, free-range, etc.). I feel that it's very difficult to know where post gallbladder removal impacts leave off and innate CFS gut issues pick up sometimes. And it can be maddening. So I end up throwing a lot of stuff at the wall, so to speak, and whatever sticks sticks. I just never really know why or what!
I wish I could tell you that I have the methylation process worked out. I do not. I've been wary of disrupting my body any more than the ongoing stress in my life already has done. BUT. I do take tons of SAM-e (part of methylation) and I take glycine. And I've taken SAM-e for decades. I can tell when I'm not taking it. I'm in more pain, upper right quadrant pain is more severe (interesting, isn't it?) and I just generally have less spark ("spark" as defined by what CFS already suppresses) and I'm less upbeat mentally, less focused. I've also focused on increasing glutathione but I know that has only been a half-way effort (if even) and can't say that the glutathione attempts have been really very helpful. Also, I take NAC regularly. I consume 3 grams of MSM daily as well (not sure how much that helps but I feel it impacts my overall energy). BUT. I've ordered a lot of supplements towards the work of re-introducing the methylation protocol. I can keep you posted as I go, if interested.
Leaky gut etc. Gut issues are just a matter of course with CFS. I take it for granted that I'll either be one extreme or the other with gut health. But something very reliable for me when IBS-D is prevalent is psyllium seed powder (and probiotics, but honestly it's mainly the psyllium seed powder that helps me, oh and sauerkraut). I do NOT mean psyllium seed husk powder. The husk powder tears at the gut and can cause bleeding. The seed powder is almost impossible to find except via Starwest Botanicals and I purchase it via Amazon and put it in pomegranate juice and in my smoothies as needed. When I began using that (I also used bentonite clay, other clays AND of all things, food grade diatomaceous earth) especially, my gut became very happy and I have since been able to reduce more carbs as a result.
Anti-virals I use: Seagate (best product) Olive Leaf Extract along with Cordyceps (for my gut, for my heart - it was the only thing that stopped non-stop PVCs, and for overall energy and inflammation relief) as well as Oil of Oregano (caution on this one, I hold a big gulp of water in my mouth and put a few drops in and swish it around as it can burn; it could also just be put in a glass of water but I've not done that since you can't control how it enters your mouth and it can hurt).
Anything that causes detox just immediately throws the red flags up in my mind so I go very cautiously, whether there's an inherent underlying risk with detox or not. Gentle and gradual is my game. Eating cleanly helps with having a body that is ready to handle any level of detox. But I imagine you know this very well.
I fear I've tossed more than you asked for out here! Hope some of this is useful.