Necator americanus (NA), human hookworm, is the most frequently used organism in Helminthic Therapy currently. The prospective host applies microscopic larvae in a water solution to the skin and the larvae migrate from there to their ultimate home, the lower intestine. NA's systemic effect has helped people with MS, CFS/ME, lupus and many other autoimmune problems. More than 700 million people host human hookworm worldwide.
In the second week, I had a "bounce". My symptoms improved, my years' long anxiety lifted and I had a new sense of optimism. The bounce only lasted a few days, but it was glorious. I returned to baseline, but new improvements appeared as the weeks passed. The worst side effects I had were increased wind and a few weeks of vague gastrointestinal unease.
By the fifth week, the brain fog I'd had for years all but disappeared. My joint pain and plantar fasciitis did too. At week ten, I had a step change in energy. Suddenly, I had several hours of useful energy most days and was staying up later. I was able to clean the house, cook food and I started contemplating tackling the garden. My migraines became less frequent, less intense and of shorter duration.