Lactoferrin Inhibits Tryptase.

Discussion in 'Mast Cell and Histamine' started by Remy, Oct 27, 2016.

  1. Remy

    Remy Administrator

    Tryptase has been in the news a bit here lately as being elevated in ME/CFS and other related illnesses.

    Tryptase is the main diagnostic criteria for systemic mastocytosis but the level is not usually elevated in MCAS.

    But it is interesting that lactoferrin strongly inhibits tryptase and thus might improve symptoms for at least a subset, especially those with asthma.

    Lactoferrin is pretty cheap and readily available as a supplement so that is all positive for a trial too.

     
    ankaa likes this.
  2. WilliamDonati

    WilliamDonati Member

    Lactoferrin is a cationic protein which binds tightly to heparin thereby inhibiting tryptase