Poll Low Alkaline Phosphatase (ALP) levels? Poll for both low and hi

Discussion in 'General Discussion' started by LittlestEngine, Jul 30, 2018.


Have you ever have abnormal Alkaline Phosphatase (ALP) tests?

  1. Yes - LOW Alp

  2. Yes - HIGH Alp

    0 vote(s)
  3. No - Normal range

    0 vote(s)
  4. No - Never teseted

  1. Hi All,

    I started having symptoms in the early 2000s and since the very start of testing whenever doctors have run a standard liver function panel my Alkaline Phosphatase (ALP) comes back low. And every time they say it is irrelevant since it only matters if it's high. But as a PhD myself who can't help but research I periodically set out to investigate and find...well, basically nothing (except mentions of malnutrition, which I suppose could be possible if there is malabsorbtion/leaky gut, and Wilson's Disease, which I don't have).

    So I'd look, find nothing, forget about it. Recently, however, I was prescribed Xyrem for sleep, and after having several horrific experiences, learned I needed to start at the dose typically recommended for those with hepatic dysfunction. Indeed I am super sensitive to most medications/supplements I take, as well as to alcohol and while there could be many reasons, it got me thinking about ALP again (which, turns out, the testing looks at overall, although ALP subtypes may be from bone, mitchochondria, other sources in addition to liver).

    Looking on this forum I noticed others have mentioned low ALP (Mellster back in 2012, Neunistiva, Winterwren, Bjjpapi this year) but others have had high. Thought I'd see about numbers.
    Not dead yet! likes this.
  2. Remy

    Remy Administrator

    I need some clarification!

    Mine is not below range ever, but is usually lower than optimal in the 50s historically.

    Since I started taking high dose zinc to bring that level up into optimal ranges, my ALP has increased into the 70s.

    So maybe I need to change my vote? :)
    Not dead yet! likes this.
  3. Hmm, I can see why those options don’t quite cover your situation! Sorry about that (and apologies for several typos - brain fog!). Helpful to know yours came up that much with zinc, my haven’t but I may need to up the dose.

    I say leave your answer for now and let’s see if we can more (hint hint to forum lurkers out there - help!)
    Remy likes this.
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