"The typical response is a peak and then the level comes down, but in the vast majority of fibromyalgia patients it's just a flat reading, with no response."
Thomas J. Romano, MD, PhD, a pain specialist based in Martins Ferry, Ohio, presented the results of a 60-person study at the American Pain Conference. The study found low blood magnesium and IGF-1 levels.
IGF-1 levels were incredibly low! NMean IGF-1 level of 59.33 ng/dL, which is lower than the mean of 235 ng/dL. Mean magnesium levels were 4.49 mg/dL, lower than the mean level in a control group of 12 osteoarthritic patients and the laboratory standard of 5.5 mg/dL.
He recommends growth hormone for the low IGG-1 levels.
"When I suspect a patient's IGF-1 levels are low, I send them to an endocrinologist for confirmation and they will do the intravenous GHRH [growth hormone–releasing hormone]-arginine stimulation test," he explained.
"The typical response is a peak and then the level comes down, but in the vast majority of fibromyalgia patients it's just a flat reading, with no response."
Treatment with growth hormone to restore normal levels typically starts with low dose, 0.2 mg, of subcutaneous injections daily for several months, with increased titration if levels are not restored within several months, Dr Romano said.
Read more including what a pain specialist said about the finding here - http://www.medscape.com/viewarticle/851314#vp_2
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