Founder of Health Rising and Phoenix Rising
The really interesting thing about Parkinson's is that it effects the substantia nigra and basal ganglia in the brain - which Miller has associated with ME/CFS. It appears to effect a different part of the basal ganglia - the part that governs movement. Dopamine is a key factor in Parkinson's and it could play a role in ME/CFS.
I do wonder if there are going to be overlaps over time...."Like a motor constantly running at high speed, these neurons need to produce an incredible amount of energy to function. They appear to exhaust themselves and die prematurely. As the disease progresses, the amount of dopamine produced in the brain decreases and the symptoms - which include tremor, slowness, stiffness and impaired balance - gradually worsen, making it increasingly difficult to walk, talk, look after oneself and have a normal life.