My guess? Toxicants. In our food, in the air, in our water...and lack of meaningful nutrition in the face of excessive calories. It all adds up and makes us vulnerable.Yeah, but what caused the mito dysfunction in the first place? Will we ever find the beginning of this?
This is the song that never ends, It just goes on and on my friends...
I see your point, but then why only us? The rest of the world is living under those conditions, not just us. Why are we the only ones with this damned disease?My guess? Toxicants. In our food, in the air, in our water...and lack of meaningful nutrition in the face of excessive calories. It all adds up and makes us vulnerable.
But fixing that root cause won't happen unless extinction and reboot.
Developing drugs that target mitochondria is challenging because it is difficult to penetrate cell and outer mitochondrial membranes. In multiple nonclinical studies, Bendavia has been shown to reach the inner mitochondrial membrane and target cardiolipin, a lipid critical to maintaining mitochondrial function and cellular energy supply. In these studies, Bendavia has been shown to promote energy production and reduce the production of excess ROS.
Mitochondrial myopathies are caused by mutations, or changes, in genes. They are inheritable, although they can occur with no family history, and they often affect members of the same family in different ways. Muscle weakness, exercise intolerance, trouble with balance, and impaired coordination are common features of mitochondrial myopathy (MM) given that muscle cells have particularly high energy needs.6
Partly, for sure. I think we all have some threshold, that is probably mostly genetically determined, for how much stress we can take before things start to break down. And I mean all sorts of stress, not just emotional stress, obviously. In fact, probably the greatest stressors right now are environmental in nature.Okay, why do we have it worse than they do? Genetics?
And high enough doses are how much, do you know? I like this idea because fish oil is readily available and relatively cheap. I'd take more in a flash if I had reason to think it would help. Do you know if there are upper limits for safety?Developing drugs to target mitochondrial membranes may be difficult, but fish oil has been proven to do this in studies...it reorganizes the lipid bilayer and improves metabolism in high enough doses.
Looks like it is still in trials, but has been granted orphan drug status.Is there any news regarding what happened with this one?