My EOS has been elevated off and on for many years (25+ years). I've never had a doctor even acknowledge that it was elevated, let alone be concerned about it. I asked about it a couple of times and they just shrugged and said it didn't mean anything, which is problem I have frequently had with other elevated readings on other blood tests. Doctors don't seem to pay much attention to EOS, but there was a television series years ago called "Northern Exposure". There was a character in it Mike Monroe (Anthony Edwards) who moved to Alaska because he had severe allergies and multiple chemical sensitivity (sound familiar?). He used to monitor his EOS because he said it was an indicator of reaction to antigens. I do have a lot of allergies, and allergies are an autoimmune problem just like CFS. (The local doctor thought he was nuts but he ran the EOS tests, and others, for him anyway. By the end of Monroe's stay in Alaska the doc started to wonder if Monroe wasn't right about the EOS levels.) I've wondered if the EOS readings are related to CFS somehow.
I couldn't find the ALS test so I don't know what that's for. Wikipedia says the elevated A1C could mean you're pre-diabetic. I looked at my most recent A1C (5.0 in range of 4.0-5.6). Right underneath the results it says, "Hemoglobin A1C values of 5.7-6.4 percent indicate an increased risk for developing diabetes mellitus." If I were you I'd start watching your ratio of carbohydrates to protein in your diet, and I'd cut back on sugar, especially added, processed sugar, wherever you can*. My sister and I did that about 15 years ago and it has helped with the CFS fatigue and helped keep our weight down. We've found that for every gram of protein we can afford 3 grams of carb. For instance, if you eat a square of cheese that has 7 grams of protein you can afford 21 grams of carbohydrate, so you could eat the number of crackers with it that would provide up to 21 grams of carbohydrate. Unprocessed carbs are less of a problem than processed ones. Cinnamon (also in capsule form) and beta-glucan can help control blood sugar, and both are over-the-counter available. If we eat more carbs than that we feel shaky and more tired. If we eat a lot of carbs we break out in a cold sweat and can pass out. The Sjögren's Syndrome Foundation published an Anti-Inflammatory diet (by Keith Wilkinson, ND) several years ago that applies to all autoimmune-inflammation type illnesses (which would include CFS and FM). It recommends cutting or eliminating sugar, starch, red meat, refined oils (i.e., cold pressed olive is good, canola oil isn't) and others. It can be found at
https://www.sjogrens.org/files/brochures/anti-inflammatory_diet.pdf .
I know that doesn't answer your question about looking at them as a group. I'm not sure if they do mean anything as a group. I'm not a doctor, but it's been my experience that they very often don't know what to do with the results either. I've been arguing with them about my RF (rheumatoid factor) results. They sent me to a rheumatologist. She said I don't have rheumatoid arthritis - yet, so she interpreted the elevated level as a "false positive". What it really means is I have Sjögren's Syndrome. It says that right on the result report, but Sjögren's is like CFS in that it takes forever to get diagnosed. Doctors really drag their heels whenever an autoimmune disease is present, and we've had a really hard time (read practically impossible) finding doctors that know anything about autoimmunity.
Hope this helps!
Kim D
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*Artificial sweetners (i.e., aspartame) are a no-no on the anti-inflammatory diet. Stevia is a good substitute, but I use about half as much. If you use it in equal amounts (1 tsp. sugar = 1 tsp. stevia) there can be an aftertaste. Xylitol and sorbitol are good too, although they can cause loose bowels or even diarrhea, so use them carefully until you find out how you react. Stevia, xylitol and sorbitol are all natural sweeteners. Evaporated cane sugar is supposed to be better than standard processed sugar. The processing makes it worse.