Just last week I got a call from a woman seeking a FMS/ CFS support group information and treatment resources. Unfortunately I closed my group 5 years ago, after leading it for 13 years. But sometimes I still get calls, and share information I accumulated through the years. And, I make sure they know about Health Rising. Interestingly, this woman has a mild scoliosis, and her one grand daughter has a more serious case. The woman I spoke with told me she had been complaining of back pain on/off for several years, but did not have chronic body- wide pain and debilitating symptoms until her doctor injected her sacroiliac joints 7 years ago. She the ( almost immediately) developed body-wide pain and symptoms that never resolved. As we talked, I began to appreciate that her original "back pain" was really sacroiliac pain - - pelvis problem, not initially a back problem. The lowest vertebra attaches to the sacrum, so people with a sacrum/ pelvis issue can experience low back pain as well. The sacrum is held in place by ligaments, bone to bone soft tissues. So, no matter how strong your muscles are, the sacrum can still be misaligned and cause major problems. Normal movement and exercise will not realign a torqued sacrum. Also, it is important to appreciate that the spinal cord is attached inside the sacrum, by the filum terminale and other soft tissue connections. The end of the spinal cord branches into many smaller nerves ( cauda equina) that pass tthrough multiple small holes in the sacrum and transmit nerve messages to the bladder, bowel, and tissues throughout the pelvis and legs. So, how can the sacrum get misaligned in the first place: pregnancy, childbirth, kicking a soccer ball, hitting the brakes, hypermobility ( like EDS), falling on your butt, and more. I used to believe that somehow the sacrum/ pelvis complex had to have an injury to get misaligned ( rotated/ dropped) , but as I learned more, I appreciated that having even a mild scoliosis can cause the sacrum to torque. Once the sacrum is "out" the effects can be body wide. The cauda equine nerves get stetched and irritated - tension can be passed directly to the spinal cord and dura - meningeal system. The neck and stability of the vertebral column is impacted. The sacrum and occiput ( lower skull bone) have a reciprocal motion, which is part of the sophisticated sacral- occipital spinal fluid pumping system. So, the occiput ( and sphenoid bone where the pituitary sits ) can rotate and cause abnormal spinal fluid pressures and flow. The jaw changes position to help compensate. The whole body is impacted. I learned all of this the 'hard way.' My B.Sc. And post graduate work in biology helped me. But it has been a long journey.