Founder of Health Rising and Phoenix Rising
Below are the main points of the study.
- The fact that the alterations in the immune factors in the ME/CFS were almost as extreme as in multiple sclerosis - a disorder characterized by severe central nervous system dysfunction - suggests a major pathology is present in the central nervous systems of ME/CFS patients.
- The low cytokine levels suggests that some sort of immune exhaustion - caused by an infection or by immune upregulation - is present in ME/CFS. These findings parallel those of the recent Hornig/Lipkin study suggesting that immune up regulation early in the disorder may lead to immune burnout later on.
- Several of the immune factors in the ME/CFS patients spinal fluid suggest an allergic type of reaction may be occurring in their CNS. That is also found in some central nervous system infections – so an infection could be driving this process.
- The immune factor most identified with the ME/CFS patients has been associated with cognitive declines, aging and reduced neuron production.