Study: Elevations of Ventricular Lactate Levels Occur in Both CFS and Fibromyalgia

[nanobug]

From the paper:

"Mean CSF (Cerebro-Spinal Fluid) lactate levels in CFS, FM and CFS+FM did not differ among the three groups, but were all significantly higher than the mean values for control subjects."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754037/

 

[Remy]

“However, the existence of elevations in ventricular lactate in both illnesses suggests a problem in brain-related mitochondrial metabolism.“

 

[nanobug]

“However, the existence of elevations in ventricular lactate in both illnesses suggests a problem in brain-related mitochondrial metabolism.“

Yeap, consistent with a shift towards aerobic glycolysis and away from mitochondrial oxidative phosphorylation. I've learned recently that this shift has a name, Warburg effect.