The danger of using Proton Pump Inhibitors (PPIs) to reduce stomach acid

[Lasse]

Proton Pump Inhibitors (PPIs) have today become one of the world's most common medications and are frequently used, among other things for chronic acid reflux (GERD). Long-term use of these drugs appears to be associated with increased mortality due to cancer, cardiovascular diseases, respiratory diseases, digestive diseases, and renal diseases.
Those using Proton Pump Inhibitors (PPIs) long-term should consider using H2 receptor antagonists (H2RAs) instead such as Famotidine to block Histamine H2 and reduce the production of stomach acid.
Always check with your doctor before using a new medicine.

Links:
Understanding the health risks and emerging concerns associated with the use of long-term proton pump inhibitors

Association of Proton Pump Inhibitor Use With All-Cause and Cause-Specific Mortality

Estimates of all cause mortality and cause specific mortality associated with proton pump inhibitors among US veterans: cohort study

Association of proton pump inhibitors with gastric and colorectal cancer risk: A systematic review and meta-analysis

H2 receptor antagonists (H2RAs) is also a medicine used for symptoms in Mast cell disorders as Mast Cell Activation Syndrome (MCAS) and the rare Systemisk mastocytose.