It breaks down to H2O (water) and O1--again making it a powerful antiseptic. As opposed to antibiotics, where bacteria can build up a resistance, they have never been able to adapt to O1.
Ozone will certainly kill pathogens by its bleaching action when used as a disinfectant. This is why in some countries such as France, they often use ozone instead of chlorine to disinfect the municipal drinking water.
However, if you look at Dr Velio Bocci's book:
OZONE. A New Medical Drug (much of this book is readable online on Amazon), or at
Bocci's paper, in the mechanisms of action of ozone that he covers, I could not find any reference to direct killing of pathogens; he seems to talk more about immunomodulatory mechanisms of ozone, which then have antiviral or antibacterial effects.
I think Bocci mentions somewhere in that book that the body's own antioxidant defenses will protect pathogens from the direct bleaching action of medically administered ozone.
And in
this paper by Bocci, he details this quenching of ozone by the antioxidant defenses:
A Detailed Description of the Action of Ozone on Whole Human Blood
Today there is no doubt that, under appropriate conditions, the blood’s antioxidant system can neutralize ozone.
In order of preference, ozone reacts with abundant PUFA, bound to albumin, antioxidants such as ascorbic and uric acids, thiol compounds with –SH groups such as cysteine, reduced glutathione (GSH) and albumin, particularly rich in –SH groups.
The main reaction:
R-CH=CH-R' + O3 + H2O → R-CH=O + R'-CH=O + H2O2
shows the simultaneous formation of one mole of hydrogen peroxide (included among reactive oxygen species, ROS) and of two moles of LOPs.
So hydrogen peroxide seems to be the main ROS generated when ozone meets the blood. But then Bocci goes on to explain that hydrogen peroxide very rapidly disappears from the blood (half life less than 2 minutes), due to the body's antioxidant defenses:
However, while in saline there is a consistent and prolonged increase, in the ozonated plasma both chemiluminescence and hydrogen peroxide increase immediately but decay very rapidly with a half-life of less than 2 min. suggesting that both antioxidants and traces of enzymes rapidly quench hydrogen peroxide. Its reduction is so fast in ozonated blood that it has been experimentally impossible to measure it.
In that same paper, Bocci also warns about the danger of ozone overdose:
If the ozone is overdosed, carbohydrates, enzymes, DNA and RNA can also be affected and because all of these compounds act as electron donor, they would undergo oxidation and serious damage.
So basically to use ozone safely, you have to employ doses that the body's own antioxidant defenses can cope with. If you go above that dose, then you start getting problems like DNA damage.
But even if ozone did have some mild direct bleaching action pathogens in the body, I don't think such killing pathogens can be the primary mechanism of action in major auto-hemotherapy using ozone, because with this approach, you only treat with ozone 200 ml of blood extracted from the body into a glass vessel, and then re-inject the treated blood back into the body.
So even if you were able to directly kill some of the pathogens in that 200 ml of blood by a direct bleaching action of ozone, but the body has around 5,000 ml of blood, plus all the tissues where pathogens can hide, so direct pathogen killing I would not have thought is the main mechanism of ozone auto-hemotherapy. Major auto-hemotherapy probably works more through an immune modulating effect.
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