HHV-6 Enzyme - Potential Biomarker for Chronic Fatigue Syndrome (ME/CFS)

Discussion in 'Chronic Fatigue Syndrome (ME/CFS) Research' started by Cort, Apr 25, 2017.

  1. Cort

    Cort Founder of Health Rising and Phoenix Rising Staff Member

    Check out who's in this below - Nancy Klimas, Mary Fletcher and Marshall Williams - three ME/CFS researchers. HHV-6 pops up again!

    Antibodies to herpesvirus dUTPase a potential biomarker for Gulf War Illness and CFS

    In All, Autoimmune Disease, Chronic Fatigue Syndrome, CNS Disease, CNS Dysfunction, Cognitive Dysfunction, Latest Scientific News by Kristin LoomisApril 23, 2017

    Herpesvirus-encoded dUTPases can trigger modulation of genes involved in chronic inflammation, T-cell function, and neurotransmitter function. A group from Ohio State University led by Maria Aziza, PhD, found that antibodies to HHV-6 and VZV dUTPases were significantly elevated in Gulf War Illness (GWI) patients compared to controls. EBV dUTPase antibodies were elevated in Chronic Fatigue Syndrome (CFS) patients.

    Also, the CFS and GWI groups exhibited increased autoimmunity; 15% of CFS and 39% of GWI patients had autoantibodies against human dUTPase, compared to 4.7% among controlsAs the herpesvirus dUTPases are only expressed during viral replication or active “abortive” infection, they are a good indicator of viral activity. 49% of CFS patients co-expressed antibodies to both HHV-6 and EBV dUTPases, and 55% were positive for HHV-6.

    Read the whole blog below


    Tammy7 and Seanko like this.
  2. Farmgirl

    Farmgirl Well-Known Member

    Interesting! Don't understand why, but I am positive for this and probably have been a long time. It would be nice to know why our bodies cannot fight these bugs, since almost all people have been exposed to this. Dr. Peterson said, if I recall correctly, that upon testing a group with ME, the spinal taps showed abnormal levels of HHV6 in the spinal fluid, Although the same virus did not show in the blood tests.

    Maria Aziza worked with Dr. Lerner before he passed away and he did a lot of research viral infections in ME and treatment with antivirals. He started I have been on AVs for 2 weeks. We'll see. My mom used to say "the proof is in the pudding".

    Some children with vaccine damage and autism are getting diagnosed with Immune Deficiency Dysfunctions. I have had two vaccine reactions I think are associated with my ME somehow. Thanks for this useful info.
  3. Seven

    Seven Well-Known Member

    DO you know if this is to the strain a or b?? or it doesn't matter?
  4. Farmgirl

    Farmgirl Well-Known Member

    Hi, gotta check my tests. I am not sure yet if it matters, but each number of HHV seems to be a different type of virus. What is yours? Whatever I have it is crazy cuz our son got a cancer at age 6 that was EBV related. Long story.