This guy is the head of a unit in the Canadian CDC. He's well respected and he's studying ME/CFS and exercise. He's got a excellent exercise physiologist working with him. That guy visited Workwell and was astonished, completely astonished to see ME/CFS patients failing the second day exercise test. He'd never seen anything like that before.
This NIH funded study is really good because it's getting us outside the ME/CFS "ghetto" so to speak and into respected researchers in their fields. That's been really hard to do with exercise. It's a smaller one-year study.
http://projectreporter.nih.gov/project_info_description.cfm?aid=8752469&icde=24069285
EXPLORING HOST GENE EXPRESSION DURING POST-EXERTIONAL SYMPTOM FLARE IN ME/CFS: A
We propose to take a fresh look at why people with ME/CFS feel profoundly tired following exercise by applying newly available gene sequencing technologies with standardized exercise testing. The exercise testing provides a measured stimulus and also allows objective categorization of patients according to their exercise response. The next generation sequencing will allow a much deeper probe of host gene expression (especially as it relates to immune signaling after exercise) than has previously been possible.
By looking for differences in those with ME/CFS and in healthy people before and after exercise challenge, we hope to identify specific patterns or response that might explain prolonged fatigue symptoms, help with diagnosis and point to pathways for therapy.
By looking for differences in those with ME/CFS and in healthy people before and after exercise challenge, we hope to identify specific patterns or response that might explain prolonged fatigue symptoms, help with diagnosis and point to pathways for therapy.
![ME/CFS lecture | Dr Nancy Klimas | 2011 [Chronic Fatigue Syndrome / SEID / New Zealand] - YouTube](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
