I am experiencing a 4th week of Having less pain and more energy. This is the longest period of time (since 2007) I have felt that pacing may actually work for me. Before this, I could not go more than 2 partial days without diving into an array of horrible CFS symptoms for 3-4 weeks at a time. (I am somewhat reluctant to post this as we all know this can be a phase....) My neurologist prescribed me MetanX (a capsule containing L-methylfolate Calcium, Pyridoxal-5-Phosphate, & Methylcobalamin) suspecting I had a MTHFR marker because my daughter gave birth to my grandson who underwent amazing fetal surgery due to Spina Bifada. Sure enough 23andMe verified I do have a genetic marker for MTHFR. The MetanX is not covered by insurance, and although most pharmacies have it, it can be found online at "Brand Direct Health Pharamcy" for significantly less in cost. Just thought I'd put this out there in case anyone else wants to give it a try.....especially if you have nerve damage. I have much less burning pain and have more energy. It has taken a couple of months taking 1 capsule twice a day to suspect this is what is making the positive difference in my health. I pray it is helpful to my CFS & Fibro family.