Arginine is out for me as it can reactivate varicella/shingles, but i am using lysine currently at 1000mg bid..
I'm finding R5P to be helpful as for getting methylation going in right direction. Also P5P and methyl B12 and Methyl Folate.
If there is an issue in the kyrienine pathway, tryptophan can go down the wrong pathway and instead of causing a calming effect in the GABA pathway causes a very agitated response going into quinolinic acid and a higher glutamate response. Could cause over activation of the autonomic nervous system. Have to figure methylation out and where your mutation could be and if it's activated or not. Taking amino acids and not knowing how you are processing them, could be a disaster. So if there is an issue in kyrienine pathway (pyrolori may be an issue) - P5P, zinc and EPO may be beneficial. There could be an imbalance between copper to zinc ratios that can contribute.
See other comments I've made on the forum about my research on this.