I also use Allegra and 1/2 Zantac at bed.Thanks so much. Your symptoms sound exactly like mine except for the Kounis. I, too, carry an epipen - have since I was a kid. I’ve made countless anaphylaxis ER trips over the years. You described well the out of control feeling along with severe anxiety and inability to think. I’ve always called it an out of body experience - like I can almost observe myself from above and have no control. (It sounds crazy unless you’ve experienced it!).
I’m amazed that Gastrocrom helps with all that. I was told it would only help with GI issues, which, while annoying, are the least of my concerns.
Do you take it 4 times per day, 30 minutes before meals? Also, how long did it take to notice an effect? Thanks.
When I first started GastroCrom I built up slowly. Only one vial 2 times a day. Then gradually went up. Initially I did go to full dose of 2 vials 4x a day at least 30 minutes before meals. Now I do it 2 or more times a day. Depends on the day. I always do the bedtime dose. Mast cells tend to degranulate worse at night and disturb sleep. Without it, there isn't much sleep. It keeps things more calm and I sleep better. Without, I wake up having "attacks" with tremors and tachycardia. Rude awakening. I also take it upon waking up. If I need the other two doses, I take them. But now 2 times a day is working.
I do think the Tramadol helps. It moderates NMDA and glutamate response. Puts you more into a parasympathetic mode and out of a sympathetic mode. It also helps balance other neurotransmitters and helps with mood. I only use 1 at bed. If it starts to not work, I go off it for at least a week - sometimes two. Then go back on it. It resets and starts working again. With a Bentyl which is a very mild muscle relaxer, also at night, it helps my FMS and other pains to calm down and I sleep better. If I have to reset the Tramadol, I go off the Bentyl too.