@RKB
I am pretty much with the retroviral and/ or EBV cause of ME/CFS. My son had ME/CFS at age 5, after a severe, documented case of EBV. For him, the EBV was primary.
I have suspicions that body structure may be a contributing cause of problems, though. Scoliosis is very common in the CFS/ ME /FM group.
There are many structural issues that can be associated with scoliosis - like small holes for the vertebral arteries in the top neck vertebrae. ( from Scoliosis and Spinal Pain Syndrome by Prof. Valentyn Serdyuk, MD. )
These structural issues may cause poor blood flow in areas , and/ or too much tension on the dura-meningeal system. Yes, both me and my son have mild scoliosis.
I don't know anything about enteroviruses, but appreciate they can do similar damage - i.e. Hit the CNS, cause carditis, hepatitis, thyroiditis, etc. etc.
Then there is Borrelia/Lyme and the coinfections. I just got diagnosed with late stage Lyme. But, I was already not well prior to the known tick bite -2010. Whew. Think it ultimately may come down to the ability of our immune systems to control so many potential infections.
So sad about Jodi. Wonder if she ever explored the Borrelia issue.