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Sleep: The ultimate immune system catch-22.
Sorry, that's auto-pap -- a cpap that adjusts pressure as needed.- Paw
- Post #7
- Forum: General Discussion
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Relax-Eze
It's possible that it's possible to overdo the Relax-eze. More research needed. The first night I tried a generous heaping (about 1.25 cc) and had a very rocky sleep (with "flu day" to follow). The first three hours were especially bad (my sleep problems usually come later in the night), so I...- Paw
- Post #10
- Forum: Stress Reduction, Pacing and Exercise
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Sleep: The ultimate immune system catch-22.
I have mild obstructive apnea, but a lot of clear-airway (central) apnea, which I'll bet is related to my autonomic neuropathy. Using the APAP machine makes a subtle, but significant difference. Without it I awake feeling heavy and empty of energy, as if at the cellular level -- so I just a get...- Paw
- Post #5
- Forum: General Discussion
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Relax-Eze
Ha, I just now got my pound of powder in the mail, so I went straight to my laptop to try to figure out how much to take. Since Dr Christopher doesn't provide guidance my first job will be to calculate how many teaspoons equals 880 mg, which is the recommended dose of the capsules. But my brain...- Paw
- Post #5
- Forum: Stress Reduction, Pacing and Exercise
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Nosology is no longer the problem
Weyland, thanks for the historical summary. Quite interesting. If I understand your thrust, you're saying there seems to be current excitement in the field about one important, particular manifestation of CFS that we might describe as ME. If so, my hope (and expectation) is that breakthroughs in...- Paw
- Post #6
- Forum: Chronic Fatigue Syndrome (ME/CFS) Research
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Nosology is no longer the problem
Well, assuming you're correct about multiple etiologies (and my gut tells me you are), there are still political considerations regarding disease perception: it can impact research interest, funding, and even the personal politics involving families and employers. But I do agree it seems...- Paw
- Post #2
- Forum: Chronic Fatigue Syndrome (ME/CFS) Research
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Relax-Eze
Thanks for the tip, Sue. Many reviews show you're not alone in swearing by this product. Since I've already had good experiences with some of the ingredients I went ahead and ordered a big bulk bag of powder from Amazon. Hopefully it'll work as well as the tincture. Same ingredients, no added...- Paw
- Post #2
- Forum: Stress Reduction, Pacing and Exercise
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New Ibuprofen with Arginine Proposed
Interesting. I'm for anything that mitigates the negative impact of pain reducers. (Famotidine is supposed to help reduce stomach ulcers when combined with ibuprofen.) BTW, my sense of the most up-to-date conclusions about the arginine/herpes connection is that it depends on the...- Paw
- Post #2
- Forum: Relieving Pain
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Why is this still happening?
I don't know the details of how projects in the UK are funded, but, in general, I applaud any researcher who, in good faith, picks at any thread of this huge tangled ball of string. Like the recent "dauer state" headlines, all new partial insights are subject to superficial misunderstandings...- Paw
- Post #4
- Forum: ME/CFS and FM News
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Why is this still happening?
Seems they're on a fishing expedition, yes, but that's the nature of scientific research. The focus here is BPD because they happened to have some relevant cross-tab data. I realize that our community is rightly advocating for much more of certain kinds of research, but that shouldn't...- Paw
- Post #2
- Forum: ME/CFS and FM News
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Liptan's Latest
Layering, as in pinpointing and addressing what one's specific issues are with sleep -- so you're not just throwing generalized aids at it. One person might only need "deep sleep promoters" (which include sub-categories), while another might also need "stress response blockers" (which could...- Paw
- Post #6
- Forum: General Discussion
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Liptan's Latest
I just finished reading Ginevra Liptan's latest book, The Fibro Manual, and thought I'd offer a micro-review. (I won't go into detail about the contents, since you can "Look Inside" via the Amazon link above.) In short, I appreciated it a lot more than I thought I would. Since hardly...- Paw
- Thread
- fibromyalgia ginevraliptan thefibromanual
- Replies: 5
- Forum: General Discussion
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The Rogue Immune Cells That Wreck the Brain
This recent New Yorker piece focuses mostly on schizophrenia, but does a great job of summarizing (and simplifying) the current state of microglia research. And, surprise, surprise -- the immune system is key. Immune-system proteins are supposed to "tag" bad cells for elimination, and then...- Paw
- Post #2
- Forum: General Discussion
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Morning Research Headlines: Benadryl, Psoriasis
@Merry - I took diphenhydramine most nights for a few years too, after several docs told me it was benign. Then, one day I suddenly stopped being able to tolerate it for some reason (gave me flu-like symptoms), so I had to stop. That's when I found out it contributed to higher glutamate levels...- Paw
- Post #3
- Forum: General Discussion
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Morning Research Headlines: Benadryl, Psoriasis
Apparently there's new evidence that anticholinergics like Benadryl (doctors' first choice for sleep assistance) may lead to Alzheimer's. Glutamate, glutamate... Meanwhile, psoriasis is confirmed to be a systemic inflammation condition, linked to a higher risk of aortic aneurysms...- Paw
- Thread
- Replies: 6
- Forum: General Discussion
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Hypersensitivity to sounds. What causes it?
I'm wondering what this hyper-sensitivity feels like. Could it be related to the dreaded "brain zaps" typically associated with withdrawal from SSNRIs? (Although I have found they can be set off by various imbalances, including GABA (the flip side of glutamate) and the dopamine chain -- not just...- Paw
- Post #19
- Forum: General Discussion
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Cause & Cure
Ugh, please, Victor, you're "proud" of her? You "knew" your infantilizing term of address would not be well-received, but you said it anyway? Seems to me that what you perceive as your no-pussyfooting "style" has been a rationale for controlling or manipulative impulses -- not great for...- Paw
- Post #71
- Forum: General Discussion
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Autonomic Dysfunction as a Result of LOW SNS/NE.
For several months now I've been taking clonidine or guanfacine nightly (rotating them), and I've been thinking they've been consistently improving my sleep quality (not just quantity). I think our brains need a certain amount of dopamine-chain activity while sleeping in order to go through... -
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Neuroprotection memantine
Interesting. I was certain I would do well with memantine (given my past reactions and symptoms), but it consistently gives me flu-like symptoms. Magnesium, however, I tolerate very well.- Paw
- Post #8
- Forum: Other Research
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The Caffeine ME/CFS and FM Poll
I've been wondering, since I got sick, why caffeine has been the only stimulant I can tolerate with some regularity in normal doses. Other stims invariably lead to "fluey" days.
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