Nimodipine (Nimotop) is
a calcium channel blocker and vasodilator. It is mostly used to suppress blood vessel spasms that can occur during cerebral hemorrhaging and vascular ischemia. It’s ability to increase blood flows in the brain (cerebral perfusion) could be helpful in ME/CFS and POTS given increasing evidence of reduced brain blood flows and possibly vasoconstricted cerebral blood vessels.
Maija Haavisto reports Dr. Jay Goldstein found Nimodipine to be one of his most effective CFS/ME medications. She reports that it has markedly improved her brainfog and puts it on her ‘definitely try’ list.
ME/CFS and FM Doctors Report
Dr. Jay Goldstein found Nimodipine to be useful, but with one notable exception (see below), no other ME/CFS experts (that I could find) have reported on it.
Nimodipine is a cornerstone drug in Dr. Kristina Downing-Orr’s approach to Chronic Fatigue Syndrome in her book “Beating Chronic Fatigue Syndrome”. A psychologist who recovered from a severe case of Chronic Fatigue Syndrome, Dr. Downing-Orr uses Nimodipine to remove brain toxins (neurotoxins) she’s believes have built up over the course of the disease. Removal of the neurotoxins increases blood flows to the HPA axis allowing it to function better.
She also uses Gingko biloba, eight glasses of filtered water a day, L-Glutamine and evening primrose oil in conjunction with Nimodipine to improve brain circulation.
She recommends starting with one quarter tablet a day for a week, adding another quarter tablet in the afternoon and slowly working your way up to one tablet total a day by week four. Some patients may need to start lower.
Some patients may also need up to two to four tablets a day for a month or more (4-5 months at the most). Bear in mind that Nimodipine is part of a step-by-step program which should be followed to produce results. Please consult Dr. Downing-Orr’s book for more.