Small Fiber Neuropathy (SFN) Fibromyalgia and ME/CFS Resource Page

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small fiber neuropathy fibromyalgia

The first problem discovered in FM was fewer nerve fibers than usual in the skin. (The dark lines are the nerve fibers). (Photomicrograph courtesy of Therapath Laboratory (NY, NY))

Small fiber neuropathy refers to the loss of small nerve fibers in the skin and eyes (and perhaps elsewhere) of approximately 45% of people with fibromyalgia and many people with chronic fatigue syndrome (ME/CFS) as well. These nerve fibers can transmit sensory and autonomic nervous system signals to the brain.

SFN could help explain the pain, central nervous system sensitization and even  autonomic nervous system problems in  FM. Check out our SFN  (and some large nerve fiber) blogs below:

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