Within days of Naviaux’s possibly groundbreaking metabolomics paper, Maureen Hanson told a SolveME/CFS Initiative webinar audience that her metabolomics study indicated ME/CFS was a hypometabolic disorder as well. Check out what she found plus learn about her exciting new mitochondrial/immune work, and about the creation of a new ME/CFS center in one of the top universities in the country.
Also check out a surprisingly long list of ongong metabolomics and read how a surprising metabolomics study could change the medical profession’s conception of depression in
Hanson’s Metabolomics ME/CFS Study Validates Naviaux’s Core Finding
It’s been awhile since communicating and I apology for my lack of keeping briefed on these CFS issues. That said, I would like to compliment you on this fabulous article regarding Hanson’s metabolomics…I am just getting started on a gluten free diet and will add folic acid to my regimen in trying to gain strength, energy and hopefully some cognitive gains tossed in for good measure. What a wonderful addition to the CFS field having Dr. Hanson onboard. And that she is a great researcher in locating top notch grant writers for necessary grants. Hope this note finds you well (enough).
Good luck with the gluten free diet. I am in the early stages of trying the paleo diet – I think it could be good. I highly recommend trying it. Good luck with everything.
Good luck with the paleo diet trial. It seems to help some people.
A step further would be the Autoimmune Protocol (AIP). It’s worth to look into if you suspect to have an autoimmune process or symptoms that are triggered by immune reactions to certain foods. Sarah Ballantyne and Mickey Trescott have great resources.
Paleo Diet troubleshooting: The paleo diet seems to be healthier and more balanced than most diets out there. However, there are people that feel worse on it. As far as I know there are two main reasons.
FODMAP intolerance: If you get more digestive symptoms. On a paleo diet people usually eat more vegetables and fruits some of which are high in FODMAPs (e.g. onions, garlic). FODMAPs are food molecules that bacteria can easily ferment to produce lots of gas in your gut which leads to bloating, stomach cramps and other symptoms. To avoid that problem you can increase your vegetable and fruit intake slowly to get your digestive system better adjusted. Take probiotics that might help with FODMAP tolerance like Lactobacillus plantarum 299v or probiotics with Bacillus clausii (e.g. Just Thrive). Or, simply limit fruits and vegetables high in FODMAPs (a strict FODMAP elimination over several months/years might also lower good bacteria in the gut).
Anyway, digestive symptoms can have many other causes.
Eating too little carbohydrates: I think many people do better when they reduce their carb intake from a standard american diet (usually in the form of sugar, wheat and corn-syrup). Also, paleo is not a low-carb diet and most people can get enough carbs on it. However, some paleo people do better when they add white rice or white potatoes back to their diet.
Personal experience: I never noticed a difference in fatigue on a paleo diet, gluten/dairy free or even an elimination diet. So I don’t follow any specific diet. However, I still like to implement some paleo principles for anti-inflammatory benefits and Weston A. Price principles for nutrient density. My joint pain is reduced from moderate/sometimes severe to slight and seldom, which I believe is mainly because of dietary changes. I used to eat high carb/low quality so there was room for improvement.
Thanks for the suggestions.
Cudos for for her metabolomics study. Here is a statement I particularly like “low energy states lend themselves to hypersensitivity reactions”. I couldn’t agree more.
Me neither! Those nerves get pretty darn twitchy!
I’d put the hypometabolism in the symptom column for now, along with many many others, since it doesn’t seem to be unique to cfs. If its signature is unique though, it could serve as a diagnostic marker. And that alone would be huge. I think they should focus on that before getting carried away with possible treatment, etc. I’m just wary of such talks ever since the xmrv fiasco.