These metabolic pathways can really be something. Pathways by their nature can be kind of all-encompassing. We could think of the bigger ones like major rivers that send out tributaries that affect multiple systems. Tryptophan and the kynurenine pathways are one of...
Is the RECOVER Initiative listening to 30 years of experience? Time will tell. The RECOVER Initiative is not just a big deal for long COVID; it’s potentially a very big deal for chronic fatigue syndrome (ME/CFS), post-treatment Lyme disease syndrome,...
Bhupesh Prusty’s goal seems to be to upend what we know about the herpesviruses, in particular, human herpesvirus-6 (HHV-6), and their relationship to chronic fatigue syndrome (ME/CFS). His Twitter handle calls him “a passionate molecular virologist who...
The big news in David Systrom’s “Neurovascular Dysregulation Underlies Exercise Intolerance in ME/CFS” talk at the CDC yesterday was that the $8 million mitochondrial drug trial had, unfortunately, failed. The ME/CFS Mitochondrial Drug Trial Fails...
The Ramsay Awards provide pilot grants that give researchers the ability to gather the data they need to apply for much larger NIH grants. As it has over the past couple of years, the Solve ME Initiative places a heavy focus on funding clinical trials that could...
The mitochondria are a big mystery in ME/CFS and fibromyalgia. Plenty of evidence – most of it from small studies, admittedly – suggests the mitochondria are involved. Nailing down exactly what’s gone wrong has not been easy given the variety of...
