The received wisdom about the pain in fibromyalgia (FM) is that it’s being produced in the central nervous system. That idea was amplified very early in “Altered Pain in the Brainstem and Spinal Cord of Fibromyalgia Patients During the Anticipation and...
Mestinon moves the needle on ME/CFS in unusual one-shot exercise study This is the most unusual clinical trial/study that I’ve come across. Too short to be a full-blown clinical trial, it was essentially a short-term test of the idea that problems with...
An $8 million clinical trial of a mitochondrial enhancer, no less, in ME/CFS? I thought I was hearing things but it was so, and, in the end, it even makes sense given how rapidly some parts of this field are moving forward. But first, a little backstory. A...
Epic ME/CFS Hypothesis Series Not many people have taken their shot at completely explaining chronic fatigue syndrome (ME/CFS), but of those that have, Wirth and Scheibenbogen’s epic three-part hypothesis series takes the cake. If the goal of a hypothesis is to...
Postural orthostatic tachycardia syndrome (POTS) has always been thought to be the big deal regarding orthostatic intolerance (increased symptoms while standing or sitting) in chronic fatigue syndrome (ME/CFS). That may be changing with a recent study,...
“Millions of people continue to suffer from exhaustion, cognitive problems and other long-lasting symptoms after a coronavirus infection. The exact causes of the illness, known as long Covid, are not known. But new research offers clues, describing the toll the...