These metabolic pathways can really be something. Pathways by their nature can be kind of all-encompassing. We could think of the bigger ones like major rivers that send out tributaries that affect multiple systems. Tryptophan and the kynurenine pathways are one of...
Another week – another fascinating drug connection pops up in long COVID. A preprint of a long-COVID study, “Outpatient treatment of Covid-19 with metformin, ivermectin, and fluvoxamine – and the development of Long Covid over a 10-month...
Nothing yet in long COVID, or PASC, has better illuminated for me the difference between the chronic fatigue syndrome (ME/CFS) and fibromyalgia (FM) field than the recent RECOVER Research Review talk on biomarkers and long COVID. (Transcript here.) The participants in...
Suzanne Vernon’s interest in pathogens and post-infectious diseases goes back to when, as a 20-year-old, she landed a work-study job at the CDC’s Division of Vector-Borne Diseases while an undergraduate at Colorado State University. Ten years later with...
The “omics” studies (genomics, metabolomics, proteomics, transcriptomics) are all the rage. These studies are attempting to get at the molecular roots of chronic fatigue syndrome (ME/CFS), but there’s a problem. ME/CFS is probably not just a...
Several studies suggest that butyrate-producing bacteria are reduced in people with chronic fatigue syndrome (ME/CFS) and possibly fibromyalgia (FM) and long COVID. The fact that three different techniques have found reduced levels of butyrate-reducing bacteria in...