Sustained Stimulation of β2- and β3-adrenergic Receptors Leads to Persistent Functional Pain and Neuroinflammation. Xin Zhang, MD, PhD, Jane E. Hartung PhD, […], and Andrea G. Nackley PhD, PhD. Brain Behav Immun 2018 Oct;73:520-532. doi:...
The neuroinflammation findings in chronic fatigue syndrome (ME/CFS) and fibromyalagia (FM), while restricted to a few studies, are still pretty compelling. We know that many, if not all of the symptoms associated with ME/CFS and FM such as fatigue, pain, cognitive...
Still at the Beginning? A recent review “Current and Emerging Pharmacotherapy for Fibromyalgia” examined the state of drug therapy for FM. It was a bluntly honest review. The news on the drug side has not been, after all, all that good in FM. A large study...
Two ME/CFS, yes, ME/CFS low dose naltrexone papers appear, one fibromyalgia report attempts to turn dosing protocols on their head, one patient blows through normal dose levels with spectacular success, Jarred Younger hunts for a more powerful naltrexone, and then...
It must have seemed like a done deal. Daiichi Sankyo was so confident that its safer, more effective version of Lyrica (pregabalin) called Mirogabalin was going to beat the pants off the best-selling drug for FM. How confident were they? They funded easily the largest...
It was a project birthed in hope. Pal Schaathun, a Norwegian filmmaker would document what he hoped might be the end of chronic fatigue syndrome (ME/CFS). That, unfortunately, turned out not to be but Schaathun ended up documenting – in strikingly beautiful...
