Lactate has become a big deal in both chronic fatigue syndrome (ME/CFS) and fibromyalgia (FM). A by-product of anaerobic energy metabolism, lactate ordinarily gets pumped out of our cells in large amounts during exertion. The lactate findings suggest that the energy...
The last of three blogs on The Solve ME/CFS Initiative focuses on the SMCI’s core mission – funding research that makes a difference in chronic fatigue syndrome (ME/CFS). Serendipity can play a major role in research and it may be doing so at the SMCI....
Producing energy is a big problem in Chronic Fatigue Syndrome (ME/CFS). In fact it’s probably the problem in ME/CFS, which is why the findings of mitochondrial dysfunction and lowered ATP production have made sense. When the metabolomics studies suggested that chronic...
The Open Medicine Foundation released two videos of Ron Davis talking about their work over the past couple of weeks. I got a chance to talk to Davis twice since then and to flesh out a bit more what he’s doing right now. As most people probably know, the Davis...
Dr. Light has said that he wants to do for fatigue what researchers have done for pain; that is uncover the molecular pathways that cause fatigue. Some time ago Light presented one of the most spectacular graphs of ME/CFS ever done. I still remember the gasp that...
Fluge and Mella seem to be working at almost lightning speed. Besides managing their huge Rituximab study (and all the sub- studies within it) and the cyclophosphamide trial, they’re also carrying out large research studies. For years, of course, some...
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