Epigenetics Study Highlights Metabolic Problems in Chronic Fatigue Syndrome (ME/CFS)
There was a time that the HPA axis was “it” in chronic fatigue syndrome. More studies have been done on the powerful glucocorticoid hormone cortisol than other factor in ME/CFS, and it’s not hard to understand why. Cortisol not only plays a major...
Global Pain, Fibromyalgia and the Insula – Ground Zero for Pain and Stimuli Issues in FM?
The “Global Pain” Diseases There are two kinds of “pain” in fibromyalgia. There’s a more ordinary kind of pain – the burning, stabbing, aching, etc. usually associated with some type of injury (even though no overt physical injuries...
The Big Fishing Expedition: Report from the NIH’s Intramural Study
The NIH’s Intramural study constitutes the biggest “fishing expedition” ever done in this disease. From stays in metabolic chambers, to ME/CFS patients immune systems being transplanted into mice, to their “brains” (neurons) being grown...
Early Results Suggest Two Radically Different Immune Subsets Present in Chronic Fatigue Syndrome (ME/CFS)
Subsets, Subsets, Subsets Everyone with ME/CFS who’s been around a bit must ask themselves at some point, “Do I have what she or he has?” Some people do great on treatments that others fail on. Some people get really, really sick while others...
An Immune Disease? Low Dose Naltrexone (LDN) Fibromyalgia Study Suggests FM Has Inflammatory Side
Low dose naltrexone (LDN) is becoming more and more widely used in fibromyalgia (FM) and chronic fatigue syndrome (ME/CFS). You can chart that use right back to Jarred Younger’s two small FM trials in 2009 and 2013. Now Younger’s back with a third trial...StudyME
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