Lactate – Is it Everywhere in Fibromyalgia and Chronic Fatigue Syndrome (ME/CFS)?
Lactate (L-lactate) is an organic compound produced during anaerobic energy metabolism. It’s constantly being formed – even when we are at rest – but is formed in higher quantities when ATP levels are low and anaerobic energy metabolism is high....
Three Pronged NIH ME/CFS Study Sets Treatments as Ultimate Goal
Dr. Avindra Nath laid out a three pronged strategy to develop treatments for ME/CFS at the CDC’s Grand Rounds meeting today. The first step is the Clinical Center Study soon to begin. The second step will validate the biomarkers found in the first study. The...
The Big NIH ME/CFS Clinical Center Study: What Do You Want In It?
Thus far the NIH’s big Clinical Center study is looking good. They’ve cleared up the definition problem and are focused on post-exertional malaise. This is a different kind of study, however, than the NIH usually does. It’s an exploratory study. ...
The NIH Clinical Center Study for Chronic Fatigue Syndrome (ME/CFS): the Good, the Bad and the Just Plain Weird
A rough sketch of the NIH’s Clinical Center study for chronic fatigue syndrome (ME/CFS) has been posted. The good news about the study is that when Francis Collins said they were serious about ME/CFS he apparently wasn’t kidding. This looks to be the most...
Diagnosing Fibromyalgia The Small Nerve Fiber Way
We’re going to take a deeper look at the oh so interesting field of small fiber neuropathy fibromyalgia (FM). A debate is raging over how big of a role SFN plays in FM. The central sensitization guys are saying probably “not much” while the immune...StudyME
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