The Itaconate Shunt hypothesis could explain why an infection produces so much fatigue, brainfog, postexertional malaise and other symptoms in chronic fatigue syndrome (ME/CFS)
It’s clear that glial cells – immune cells found in the brain and the spinal cord – play an important role in producing chronic pain and neuro-inflammation. Glial cell activation in the brain is often measured using the levels of a benzodiazepine...
A case study suggests fibromyalgia patients might want to look beyond the 'big three' (Lyrica, Cymbalta, Savella) to Topomax and other lesser-known drugs.
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