At the Emerge Conference Paul Fisher provides evidence of mitochondrial dysfunction in chronic fatigue syndrome aka ME/CFS. Complex V problems cause the mitochondria to poop out under stress - resulting in widespread attempts across the other complexes to compensate - and potentially explainiing the post-exertional malaise or PEM in ME/CFS
Tony Komaroff's wildly popular chronic fatigue syndrome (ME/CFS) unifying model paper published in JAMA - the top medical journal in the world - suggests ME/CFS is hypometabolic state brought on by neuroinflammation or is a hibernation-like state.
Few studies ten years ago considered the gut and its flora in the context of chronic disease. Now microbiome studies are popping up in just about every disease. The “gut-brain” axis is a real thing. The bacteria in the gut appear to be able to affect brain...
If there was ever a “prodigal virus” in ME/CFS, it would be the Epstein-barr virus (EBV). Since the first EBV ME/CFS study in 1984, dozens of studies have examined the role the virus may play in this diseases, and tens of thousands have studied its...
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