Tony Komaroff's wildly popular chronic fatigue syndrome (ME/CFS) unifying model paper published in JAMA - the top medical journal in the world - suggests ME/CFS is hypometabolic state brought on by neuroinflammation or is a hibernation-like state.
Few studies ten years ago considered the gut and its flora in the context of chronic disease. Now microbiome studies are popping up in just about every disease. The “gut-brain” axis is a real thing. The bacteria in the gut appear to be able to affect brain...
In Part III of Kyle McNease’s narrative of going from abundant health to a severe case of ME/CFS, and then back to relative health, a loss hits Kyle hard, he ponders the fact that life didn’t realize he had other plans, and he comes to a surprising realization...
In Part II of Kyle McNease’s narrative of going from abundant health to a severe case of ME/CFS, and then back to relative health, Kyle experiences abandonment, takes a surrealistic a trip to a psychiatrist, and reflects on the scars his illness has left on his...
If there was ever a “prodigal virus” in ME/CFS, it would be the Epstein-barr virus (EBV). Since the first EBV ME/CFS study in 1984, dozens of studies have examined the role the virus may play in this diseases, and tens of thousands have studied its...
(Kyle’s story of going from abundant health to a very severe case of ME/CFS, and then, when all looked bleakest, back to relative health, almost defies description. The length of his narrative, the elegance and directness of his writing, even the difficulty it...
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