Studies indicate that the nasal congestion and mid-facial pain found in the chronic fatigue syndrome (ME/CFS) is probably not due to inflammation or mast cell activation but instead is probably caused by small nerve fiber problems and dysautonomia.
A 2-day exercise test found people with chronic fatigue syndrome get weaker after exercise while healthy people get stronger. People with ME/CFS had higher lactate levels and reduced energy production on the second exercise test while healthy controls had lower lactate levels and maintained their performance.
A study suggested that the Myhill mitochondrial tests for chronic fatigue syndrome which laid the basis for three studies and Dr. Myhill's treatemnt protocol were inaccurate and should be interpreted "with caution".
How close are we to understanding chronic fatigue syndrome (ME/CFS) when we can accurately predict how the greatest stressor of all – exercise – affects ME/CFS patients’ physiology? Nothing, after all, whacks a person with ME/CFS like exercise....
Similar metabolic and endocrinological findings in chronic fatigue syndrome and overtraining syndrome suggest the two diseases - both defined by an inability to exercise - may be similar
With regards to research funding, infrastructure development, creativity and sheer energy - there's no doubt that the smaller ME/CFS community is far ahead of the much larger fibromyalgia community. The question is why and what can be done to unleash the FM community's vast resources.
A BIG thanks to the 217 people whose $16K in donations made Health Rising's drive a success :)
Stay Up to Date with ME/CFS, Long COVID and Fibromyalgia News
Get Health Rising's free blogs featuring the latest findings and treatment options for the ME/CFS, long COVID, fibromyalgia and complex chronic disease communities.