Sleep disturbances and severe stress as glial activators: key targets for treating central sensitization in chronic pain patients?Jo Nijs,Marco L. Loggia,Andrea Polli,Maarten Moens,Eva Huysmans,Lisa Goudman, Expert Opinion on Therapeutic Targets Volume 21, 2017...
Poor sleep is synonymous with both ME/CFS and fibromyalgia. We know it produces fatigue, pain, irritation and mood issues but recent studies suggest that may just be the beginning of the problem. In fact, they suggest that poor sleep may have profound effects on our...
The “Global Pain” Diseases There are two kinds of “pain” in fibromyalgia. There’s a more ordinary kind of pain – the burning, stabbing, aching, etc. usually associated with some type of injury (even though no overt physical injuries...
Lactate has become a big deal in both chronic fatigue syndrome (ME/CFS) and fibromyalgia (FM). A by-product of anaerobic energy metabolism, lactate ordinarily gets pumped out of our cells in large amounts during exertion. The lactate findings suggest that the energy...
The last of three blogs on The Solve ME/CFS Initiative focuses on the SMCI’s core mission – funding research that makes a difference in chronic fatigue syndrome (ME/CFS). Serendipity can play a major role in research and it may be doing so at the SMCI....
Inflammation – Neuro and Otherwise Inflammation has become an increasingly important topic in fibromyalgia. It’s clear that “central sensitization” – an increase in pain sensitivity engineered by the central nervous system – is...
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