Mackay and Tate propose that neuroinflammation in the hypothalamus disregulates the paraventricular nucleus causing the stress response in chronic fatigue syndrome to go bananas, producing all sorts of symptoms. They look forward to the day when brain scans will produce a diagnosable brain signature for both ME/CFS and FM.
Intranasal preparations could speed the delivery of drugs and supplements like glutathione and insulin to the brain in chronic fatigue syndrome and fibromyalgia and reduced inflammation there.
The Loggia Lab at Harvard finds the same kind of widespread neuroinflammation in Gulf War illness that it did in fibromyalgia. Similar patterns of unusually widespread neuroinflammation have been found in chronic fatigue syndrome and migraine.
In a ISEAI presentation, Dr. Mary Ackerley talks about how environmental stressors such as mold, pathogens and toxins can trigger neuroinflammation and produce the symptoms found in ME/CFS, FM and similar diseases. Mary Ackerley MD is not your ordinary summa cum laude...
How close are we to understanding chronic fatigue syndrome (ME/CFS) when we can accurately predict how the greatest stressor of all – exercise – affects ME/CFS patients’ physiology? Nothing, after all, whacks a person with ME/CFS like exercise....
The failure of the BACE drugs has some drug companies looking for ways to reduce neuroinflammation - which appears to be present in chronic fatigue syndrome and fibromyalgia
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