The 2020 IACFS/ME Zoom conference found evidence of B-cell abnormalities that might be tied to autoimmunity, problems with mitochondrial energy production and a finding which suggested that having more uplifiting events may actually help.
An immune hole may have predisposed people to getting chronic fatigue syndrome and another study is underway to assess COVID-19 patients. A breakdown in the citric acid cycle is impairing energy production and producing increased lactate as well. Plus the blood of ME/CFS patients appears to contain a substance which triggers cells to use up energy and produce lactate....
Bhupesh Prusty and Bob Naviaux team up to show that a simmering herpesvirus infection could produce the key features of the "cell danger response" where a mitochoncrial breakdown and immune activation combine to sap chronic fatigue syndrome patients' energy.
A large French study finds abnormally high lactate levels in ME/CFS even at rest…sometimes. David Systrom seemed to call it out – his invasive CPET results suggested that mitochondrial dysfunction was present in a large subset of people with chronic...
Poor oxygen uptake from the red blood cells could help explain the exercise issues in chronic fatigue syndrome (ME/CFS). Mitochondrial problems or hyperventilation contribute to the oxygen uptake problem.
A study suggested that the Myhill mitochondrial tests for chronic fatigue syndrome which laid the basis for three studies and Dr. Myhill's treatemnt protocol were inaccurate and should be interpreted "with caution".
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