Explaining ME/CFS? Prusty / Naviaux Study Ties Infections to Energy Breakdowns
Bhupesh Prusty and Bob Naviaux team up to show that a simmering herpesvirus infection could produce the key features of the "cell danger response" where a mitochoncrial breakdown and immune activation combine to sap chronic fatigue syndrome patients' energy.
Lactate Levels Elevated Even at Rest In ME/CFS?
A large French study finds abnormally high lactate levels in ME/CFS even at rest…sometimes. David Systrom seemed to call it out – his invasive CPET results suggested that mitochondrial dysfunction was present in a large subset of people with chronic...
Poor Oxygen Extraction is Contributing to Exercise Intolerance in Chronic Fatigue Syndrome (ME/CFS)
Poor oxygen uptake from the red blood cells could help explain the exercise issues in chronic fatigue syndrome (ME/CFS). Mitochondrial problems or hyperventilation contribute to the oxygen uptake problem.
The Myhill Mitochondrial Test and ME/CFS Studies Take a Hit
A study suggested that the Myhill mitochondrial tests for chronic fatigue syndrome which laid the basis for three studies and Dr. Myhill's treatemnt protocol were inaccurate and should be interpreted "with caution".
Emerging Insights #II: “The Cellular Equivalent of Chronic Fatigue” Found in ME/CFS
At the Emerge Conference Paul Fisher provides evidence of mitochondrial dysfunction in chronic fatigue syndrome aka ME/CFS. Complex V problems cause the mitochondria to poop out under stress - resulting in widespread attempts across the other complexes to compensate - and potentially explainiing the post-exertional malaise or PEM in ME/CFSStudyME
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