Solve ME's Ramsay Awards fund pilot studies into T-cells, Class II MHC molecules, the microbiome/virome, the autonomic nervous system and brain blood perfusion and functionality in chronic fatigue syndrome.
Problems within the brainstem and mid-brain could be causing movement, sleep, alertness and autonomic nervous system issues in chronic fatigue syndrome
Stanford researchers have identified specific neurons in the amygdala which produce the unpleasantness which makes pain sensations so intolerable. They're now searching for ways to turn off those neurons and relieve the hurt for people in chronic pain. .
Studies indicate that the nasal congestion and mid-facial pain found in the chronic fatigue syndrome (ME/CFS) is probably not due to inflammation or mast cell activation but instead is probably caused by small nerve fiber problems and dysautonomia.
How close are we to understanding chronic fatigue syndrome (ME/CFS) when we can accurately predict how the greatest stressor of all – exercise – affects ME/CFS patients’ physiology? Nothing, after all, whacks a person with ME/CFS like exercise....
The failure of the BACE drugs has some drug companies looking for ways to reduce neuroinflammation - which appears to be present in chronic fatigue syndrome and fibromyalgia
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