How Nucynta – an Opioid Drug – Told Us Something About the Small Fiber Neuropathy in Fibromyalgia
Nucynta, an opioid drug, was effective in reducing pain in fibromyalgia patients without small fiber neuropathy but was not effective in do so in FM patients with SFN.
Surprise Gene Finding Could Give Pathogens and Toxins a Leg Up in ME/CFS
High rates of alterations in the genes that produce mucosal proteins suggest that a damaged mucous layer in the eyes, nose or upper respiratory systems of people with chronic fatigue syndrome could be providing pathogens or toxins easier entry - possibly producing neuroinflammation and central sensitization.
Is Fibromyalgia and Chronic Fatigue Syndrome Actually Small Fiber Polyneuropathy?
Chronic fatigue syndrome (ME/CFS) and fibromyalgia (FM) produce so many symptoms that diagnosing them can be difficult for uninformed doctors. While we know that small fiber polyneuropathy (SFPN) (or small fiber neuropathy (SFN) commonly occurs in both these diseases,...
More is Not Better: Increased Small Nerve Fiber Problems in Fibromyalgia Spell Trouble
Some studies a field waits for – and this is one. The past nerve fiber studies in fibromyalgia (FM) have tended to be small and use different methods and criteria – making it difficult to be clear about the extent of the problem. When a field gets to a...
Is the Brain Causing the Small Fiber Neuropathy in Fibromyalgia (and ME/CFS?)
The damage to the small nerve fibers in the skin and eyes of people with fibromyalgia has long been assumed to be caused some process in the body. Recent studies, though, suggest that, surprisingly enough, the brain could be trying to protect itself by eliminating nerve fibers in the body.StudyME
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