Surprise Gene Finding Could Give Pathogens and Toxins a Leg Up in ME/CFS
High rates of alterations in the genes that produce mucosal proteins suggest that a damaged mucous layer in the eyes, nose or upper respiratory systems of people with chronic fatigue syndrome could be providing pathogens or toxins easier entry - possibly producing neuroinflammation and central sensitization.
Could Neuroinflammation Be Triggering the Cortisol Issues in ME/CFS and Fibromyalgia?
“Therefore, in this study, we hypothesize that understanding cortisol patterns in both these syndromes may be a crucial factor in characterizing FMS and CFS.” The authors More than any other substance, cortisol demonstrates how integral a role the stress...
From Fight/Flight to Neuroinflammation: Explaining the “Functional Pain” in Fibromyalgia and ME/CFS?
Fibromyalgia, chronic fatigue syndrome and other functional pain disorders may triggered by an overactive fight/flight system which results in neuroinflammation.
A Novel Neuroinflammatory Paradigm for Chronic Fatigue Syndrome (ME/CFS)
Mackay and Tate propose that neuroinflammation in the hypothalamus disregulates the paraventricular nucleus causing the stress response in chronic fatigue syndrome to go bananas, producing all sorts of symptoms. They look forward to the day when brain scans will produce a diagnosable brain signature for both ME/CFS and FM.
Are Intranasal Drugs the Future for ME/CFS and Fibromyalgia?
Intranasal preparations could speed the delivery of drugs and supplements like glutathione and insulin to the brain in chronic fatigue syndrome and fibromyalgia and reduced inflammation there.StudyME
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